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Ab-10 Rapid Labeling Kits
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ProFoldin-DPPC Liposome
TriLink 專題演講:CleanCap M6
TriLink mRNA應用線上講座影片
TriLink mRNA基礎知識系列講座影片
CleanCap M6
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GeneCopoeia-OmicsArray™ Antigen Microarray
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Viral Clearence-MockV® RVLP Kit
Viral Clearence-MockV™ MVM Kit
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Process-Related Impurity
Residual Protein A
Host Cell DNA
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qPCR Detection Method
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2022/11/11
【FUJIFILM Irvine Scientific】PRIME-XV Stem FreezIS DMSO-Free,可實現的DMSO-Free療法!
專注於開發製造無血清、化學成份確立 (chemically defined) 細胞培養基的頂尖供應商--
FUJIFILM Irvine Scientific, Inc.,
,旗下所生產的PRIME-XV Stem FreezIS DMSO-Free細胞凍存培養基於近日獲得美國FDA批准用於由Vitro Biopharma所發起的臨床試驗。
(參考資料:
https://www.businesswire.com/news/home/20221019005688/en/
)
許多新創公司與醫學專家對於如何開發新一代幹細胞療法都有完整的願景;但是如何選用安全有效的賦形劑 (excipient),以在整個試驗過程確保患者安全則是重中之重。傳統於實驗室所使用的細胞凍存培養基具有生物毒性,如:dimethylsulfoxide (DMSO),長時間或高濃度的暴露會造成細胞損傷進而產生安全性疑慮,對於臨床實踐形成嚴峻挑戰。PRIME-XV Stem FreezIS DMSO-Free為一款無DMSO、化學成份確立的細胞凍存培養基,可應用於凍存人類間葉幹細胞 (Mesenchymal Stem Cells, MSCs)、人類造血幹細胞 (Human Hematopoietic Stem Cell) 與前驅細胞 (Human Progenitor Cells, HSPCs) 並可完整保存細胞活性與分化潛勢,在越加精密的嶄新醫療時代,成為加速幹細胞療法於臨床實踐的驅動力。
產品特點:
● 於冷凍後可完整保存幹細胞的分化潛能與細胞活性。
● 可取代DMSO,利於開發新一代更具潛力的幹細胞療法。
● 無動物來源,化學成份確立 (chemically-defined) 的安全細胞凍 存液。
● 使細胞可於-80 °C至-196 °C 的極低溫環境下保存。
● cGMP規範下生產製造。
● 原料藥主檔案 (DMF) 註冊。
● 可進行包裝與其餘規格客製化。
※ 僅供研究用途與後續製造使用
✱
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